HUMIRA targets and blocks a specific source of inflammation that contributes to ankylosing spondylitis symptoms


With ankylosing spondylitis, your body over-produces an inflammation-causing protein called TNF

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HUMIRA targets and helps block TNF, reducing its inflammatory effects on the joints, which lead to the symptoms of joint pain, swelling and stiffness seen in ankylosing spondylitis.

Getting results with HUMIRA

You can expect to see improvement in signs and symptoms of ankylosing spondylitis in as little as 2 weeks in some people, however it may take up to 3 months or longer to notice improvement.1,2,§ You’ll need to be patient and stay on track with your dosing schedule. Some patients may not respond within these timeframes.



What is HUMIRA and how does it work?

HUMIRA (adalimumab) belongs to a group of medicines called biologics. Biologics are injectable protein-based therapies (often antibodies), which have been developed through genetic engineering (DNA technology). HUMIRA binds to a specific protein, tumour necrosis factor (TNF), which is present at increased levels in inflammatory conditions such ankylosing spondylitis. Inflammation associated with ankylosing spondylitis can be caused by an over-production of the protein tumour necrosis factor (TNF). Ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis, Crohn’s disease, and psoriasis are examples of autoimmune diseases. The cause of autoimmune diseases is currently not well understood but it has been found that increased levels of a protein called TNF plays a key role in the excessive inflammation that is a feature of these diseases. TNF triggers inflammation as part of the body’s normal immune system response, however extra TNF can attack normal, healthy body tissue and cause inflammation.

Will HUMIRA cure my disease?

Unfortunately, currently there are no treatments available that can cure ankylosing spondylitis, rheumatoid arthritis, psoriatic arthritis, polyarticular juvenile idiopathic arthritis, Crohn’s disease, or psoriasis. HUMIRA will not cure your condition but can help with your symptoms.

What else can I do to take care of my disease besides taking medications?

To better manage your disease, it may be helpful to maintain a healthy diet, get adequate rest and lose any excess weight. It’s also a good idea to exercise regularly, which can help build flexibility and strength. Always consult your doctor before beginning any diet or exercise programme.

Talk with your doctor

We’ve put together a checklist that you can take along to your rheumatologist visit to discuss symptoms and treatment options.

Take the ‘Ankylosing spondylitis symptom checker’

Take the symptom checker