HUMIRA targets and blocks a specific source of inflammation that contributes to Crohn’s disease symptoms


Crohn’s disease has been linked to an overproduction of certain proteins, including one called TNF, which is produced naturally by your body’s immune system

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HUMIRA is a biologic medication that targets and helps block TNF, reducing its inflammatory effects on the gastrointestinal tract (GI tract or tummy).

Getting results with HUMIRA

Based on clinical trials, it is expected that around half of adults with Crohn’s disease (that have not previously been given a biologic) may clinically respond or achieve remission (little or no symptoms) after just four weeks of starting HUMIRA.3,4,§ In some people, achieving clinical remission can take longer. It is possible that no effect is seen after Humira treatment. Discuss your expectations with your doctor.



What is HUMIRA and how does it work?

HUMIRA (adalimumab) belongs to a group of medicines called biologics. Biologics are injectable protein-based therapies (often antibodies).

HUMIRA binds to a specific protein, tumour necrosis factor (TNF), which is present at increased levels in inflammatory conditions such as Crohn’s disease. Inflammation associated with Crohn’s disease can be caused by an over-production of the protein tumour necrosis factor (TNF).

Crohn’s disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, and psoriasis are some examples of autoimmune diseases.

The cause of autoimmune diseases is currently not fully understood but it has been found that increased levels of a protein called TNF plays a key role in the excessive inflammation that is a feature of these diseases. TNF triggers inflammation as part of the body’s normal immune system response, however extra TNF can attack normal, healthy body tissue and cause tissue damage.

HUMIRA binds to TNF and helps reduce the pain and inflammation associated with autoimmune diseases.

Will HUMIRA cure my disease?

Unfortunately, currently there are no treatments available that can cure Crohn’s disease, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, or psoriasis. HUMIRA will not cure your condition but can help with your symptoms.

What else can I do to take care of my disease besides taking medications?

To better manage your disease, changes in your diet and lifestyle may help control your symptoms and lengthen the time between flare-ups. Certain foods and beverages may aggravate your signs and symptoms, especially during a flare-up. It can be helpful to keep a food diary to keep track of what you’re eating, as well as how you feel. If you find some foods are causing flare-ups, you can try and eliminate them. For example, limit dairy products, try low-fat foods, limit fiber, if it’s a problem food. Stress doesn’t cause Crohn’s disease, but it can make your signs and symptoms worse and may trigger flare-ups. There are helpful ways to manage stress for example, exercise – talk to your doctor about an exercise plan that’s right for you. Quitting smoking can improve the overall health of your digestive tract, as well as provide many other health benefits.

Talk with your doctor

We’ve put together a checklist that you can take along to your gastroenterologist visit to discuss symptoms and treatment options.

Download your ‘Getting ready for your gastroenterologist visit’ guide.

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