HUMIRA targets and blocks a specific source of inflammation that contributes to juvenile idiopathic arthritis symptoms


One factor involved in juvenile idiopathic arthritis is the production of too much of a protein called TNF

This extra TNF can cause inflammation, which can contribute to the joint pain, swelling, and stiffness of JIA.

Read the video transcript

HUMIRA is a biologic medication that targets and helps block TNF, reducing its inflammatory effects on the joints and the symptoms of joint pain, swelling, and stiffness.

Getting results with HUMIRA

Based on clinical study results, you may expect HUMIRA (potentially in combination with other prescribed medications) to lead to improvements in your child’s symptoms by week 16, however it may be sooner or take longer.2,3,§ 



What is HUMIRA and how does it work?

HUMIRA (adalimumab) belongs to a group of medicines called biologics. Biologics are injectable protein-based therapies (often antibodies), which have been developed through genetic engineering (DNA technology). HUMIRA binds to a specific protein, tumour necrosis factor (TNF), which is present at increased levels in inflammatory conditions such as polyarticular juvenile idiopathic arthritis. Inflammation associated with polyarticular juvenile idiopathic arthritis can be caused by an over-production of the protein tumour necrosis factor (TNF).

What else can I/my child do to take care of my/their disease besides taking medications?

To better manage your/their disease, it may be helpful to get regular exercise. Exercise is important because it promotes both muscle strength and joint flexibility.

Eat well. Some children with arthritis have poor appetites. Others may gain excess weight due to medications or physical inactivity. A healthy diet can help maintain an appropriate body weight and ensure an adequate calcium intake because children with JIA are at risk of developing weak bones (osteoporosis) due to the disease, use of corticosteroids, and decreased physical activity and weight bearing.

Apply cold or heat. Some children respond well to cold packs, others to hot packs, a hot bath or shower to ease stiffness.

Always consult your doctor before beginning any diet or exercise programme.